Bar-Lev High-Tech-Park צור קשר תפריטסגור

מעוניינים לשמוע עוד? צרו קשר


רם לוינסון
מנהלת האתר

Adva Biotechnology


According to the United States National Cancer Institute (NCI), the number of new cancer cases in the USA per year is expected to rise to 23.6 million by 2030. Cancer treatment had evolved in recent years from unspecific aggressive treatments such as radiotherapy and chemotherapy to new and more specific immune therapies. These immune therapies are usually antibodies that ether recruit the immune system to attach the tumor or block the tumor immune suppression. In recent years new therapies had evolved called immune cell therapy or Adaptive Cell Transfer (ACT), these therapies aim to activate and “educate” the immune system to attach the tumor. CAR-T (Chimeric Antigen Receptor) is one such therapy in which T cells from the patient are activated, expanded, “engineered” outside the body and reinfused to the patient. Such therapies have shown unprecedent clinical efficacy in Leukemia where above 80% of end stage patients showed remission. The results were so outstanding, that the therapies had been approved for treatment after phase 2 only. The main drawback is that the therapy is very limited both in scale and in cost (about $400,000-500,000 per treatment).

Currently, the therapy is manufactured in clean rooms manually and therefore very expensive and rarely available with a maximum capacity of a few thousand patients annually.


The solution – “ADVA X3”

An innovative, robust and modular cell manufacturing cGMP system based on a single use “end to end” solution. Enabling autologous cell therapy manufacturing at bed side, allowing optimization, tight quality assurance, availability, shortening time to market and dramatic cost reduction.

Adva Biotechnology had developed the ADVA X3 device and plans to soft launch it commercially in Q1/2020.